For recent publicatoins see here


Cytokinin signalling regulates organ identity via the AHK4 receptor in Arabidopsis

M Pernisova, M Grochova, T Konecny, L Plackova, D Harustiakova, ...

Development 145 (14), dev163907


Cell type boundaries organize plant development. Monica Pia Caggiano, Xiulian Yu, Neha Bhatia, Andre Larsson, Hasthi Ram, Carolyn K Ohno, Pia Sapple, Elliot Meyerowitz, Henrik Jonsson, Marcus G Heisler. (2017).

Elife 2017;6:e27421 DOI: 10.7554/eLife.

The shady side of leaf development: the role of the REVOLUTA/KANADI1 module in leaf patterning and auxin-mediated growth promotion

P Merelo, EB Paredes, MG Heisler, S Wenkel

Current opinion in plant biology 35, 111-116


Merelo P, Paredes EB, Heisler MG, Wenkel S. (2016)

The shady side of leaf development: the role of the REVOLUTA/KANADI1 module in leaf patterning and auxin-mediated growth promotion.

Curr. Opin. Plant Biol. 35:111-116. doi: 10.1016/j.pbi.2016.11.016

Bhatia N, Bozorg B, Larsson A, Ohno C, Jönsson H, Heisler MG. (2016)

Auxin Acts through MONOPTEROS to Regulate Plant Cell Polarity and Pattern Phyllotaxis.

Curr. Biol. 26(23):3202-3208. doi: 10.1016/j.cub.2016.09.044

Merelo P, Ram H, Pia Caggiano M, Ohno C, Ott F, Straub D, Graeff M, Cho SK, Yang SW, Wenkel S, Heisler MG. (2016)

Regulation of MIR165/166 by class II and class III homeodomain leucine zipper proteins establishes leaf polarity.

Proc. Natl. Acad. Sci. U.S.A. 113(42):11973-11978. doi: 10.1073/pnas.1516110113

Shi B, Zhang C, Tian C, Wang J, Wang Q, Xu T, Xu Y, Ohno C, Sablowski R, Heisler MG, Theres K, Wang Y, Jiao Y. (2016)

Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.

PLoS Genet. 12(7) doi: 10.1371/journal.pgen.1006168


Rast-Somssich MI, Broholm S, Jenkins H, Canales C, Vlad D, Kwantes M, Bilsborough G, Dello Ioio R, Ewing RM, Laufs P, Huijser P, Ohno C, Heisler MG, Hay A, Tsiantis M. (2015)

Alternate wiring of a KNOXI genetic network underlies differences in leaf development of A. thaliana and C. hirsuta.

Genes Dev. 29(22):2391-2404. doi: 10.1101/gad.269050.115


Heisler MG, Ohno C. (2014)

Live-imaging of the Arabidopsis inflorescence meristem

Methods Mol. Biol. 1110:431-440. doi: 10.1007/978-1-4614-9408-9_25


Brennecke P, Anders S, Kim JK, Kołodziejczyk AA, Zhang X, Proserpio V, Baying B, Benes V, Teichmann SA, Marioni JC, Heisler MG. (2013)

Accounting for technical noise in single-cell RNA-seq experiments

Nat. Methods 10(11):1093-1095. doi: 10.1038/nmeth.2645

Sappl PG, Heisler MG. (2013)

Live-imaging of plant development: latest approaches

Curr. Opin. Plant Biol. 16(1):33-40. doi: 10.1016/j.pbi.2012.10.006

Merelo P, Xie Y, Brand L, Ott F, Weigel D, Bowman JL, Heisler MG, Wenkel S. (2013)

Genome-wide identification of KANADI1 target genes

PLoS ONE 8(10):e77341. doi: 10.1371/journal.pone.0077341

Yadav RK, Perales M, Gruel J, Ohno C, Heisler M, Girke T, Jönsson H, Reddy GV. (2013)

Plant stem cell maintenance involves direct transcriptional repression of differentiation program

Mol. Syst. Biol. 9:654. doi: 10.1038/msb.2013.8


Federici F, Dupuy L, Laplaze L, Heisler M, Haseloff J. (2012)

Integrated genetic and computation methods for in planta cytometry

Nat. Methods 9(5):483-485. doi: 10.1038/nmeth.1940

Chickarmane VS, Gordon SP, Tarr PT, Heisler MG, Meyerowitz EM. (2012)

Cytokinin signaling as a positional cue for patterning the apical-basal axis of the growing Arabidopsis shoot meristem

Proc. Natl. Acad. Sci. U.S.A. 109(10):4002-4007. doi: 10.1073/pnas.1200636109


Heisler MG, Hamant O, Krupinski P, Uyttewaal M, Ohno C, Jönsson H, Traas J, Meyerowitz EM. (2010)

Alignment between PIN1 polarity and microtubule orientation in the shoot apical meristem reveals a tight coupling between morphogenesis and auxin transport

PLoS Biol. 8(10):e1000516. doi: 10.1371/journal.pbio.1000516


Hamant O, Heisler MG, Jönsson H, Krupinski P, Uyttewaal M, Bokov P, Corson F, Sahlin P, Boudaoud A, Meyerowitz EM, Couder Y, Traas J. (2008)

Developmental patterning by mechanical signals in Arabidopsis

Science 322(5908):1650-1655. doi: 10.1126/science.1165594


Gordon SP, Heisler MG, Reddy GV, Ohno C, Das P, Meyerowitz EM. (2007)

Pattern formation during de novo assembly of the Arabidopsis shoot meristem

Development 134(19):3539-3548. doi: 10.1242/dev.010298

Michniewicz M, Zago MK, Abas L, Weijers D, Schweighofer A, Meskiene I, Heisler MG, Ohno C, Zhang J, Huang F, Schwab R, Weigel D, Meyerowitz EM, Luschnig C, Offringa R, Friml J. (2007)

Antagonistic regulation of PIN phosphorylation by PP2A and PINOID directs auxin flux

Cell 130(6):1044-1056. doi: 10.1016/j.cell.2007.07.033

Heisler MG, Jönsson H. (2007)

Modelling meristem development in plants

Curr. Opin. Plant Biol. 10(1):92-97. doi: 10.1016/j.pbi.2006.11.005


Heisler MG, Jonsson H. (2006)

Computer modeling of plant development.

J Plant Growth Regul 25:267-269. doi: 10.1007/s00344-006-0080-z

Heisler MG, Jonsson H. (2006)

Modeling auxin transport and plant development.

J Plant Growth Regul 25:302-312. doi: 10.1007/s00344-006-0066-x

Brewer PB, Heisler MG, Hejátko J, Friml J, Benková E. (2006)

In situ hybridization for mRNA detection in Arabidopsis tissue sections

Nat Protoc 1(3):1462-1467. doi: 10.1038/nprot.2006.226

Friml J, Benfey P, Benková E, Bennett M, Berleth T, Geldner N, Grebe M, Heisler M, Hejátko J, Jürgens G, Laux T, Lindsey K, Lukowitz W, Luschnig C, Offringa R, Scheres B, Swarup R, Torres-Ruiz R, Weijers D, Zazímalová E. (2006)

Apical-basal polarity: why plant cells don't stand on their heads.

Trends Plant Sci. 11(1):12-14. doi: 10.1016/j.tplants.2005.11.010

Gor V, Shapiro BE, Jonsson H, Heisler M, Reddy GV, Meyerowitz EM, Mjolsness E. (2006)

A software architecture for developmental modeling in plants: The computable plant project.

In: Kolchanov N, Hofestaedt R, Milanesi L (eds.), Bioinformatics of Genome Regulation and Structure II. pp 345-354.doi: 10.1007/0-387-29455-4_33

Jönsson H, Heisler MG, Shapiro BE, Meyerowitz EM, Mjolsness E. (2006)

An auxin-driven polarized transport model for phyllotaxis

Proc. Natl. Acad. Sci. U.S.A. 103(5):1633-1638. doi: 10.1073/pnas.0509839103


Heisler MG, Ohno C, Das P, Sieber P, Reddy GV, Long JA, Meyerowitz EM. (2005)

Patterns of auxin transport and gene expression during primordium development revealed by live imaging of the Arabidopsis inflorescence meristem

Curr. Biol. 15(21):1899-1911. doi: 10.1016/j.cub.2005.09.052

Jönsson H, Heisler M, Reddy GV, Agrawal V, Gor V, Shapiro BE, Mjolsness E, Meyerowitz EM. (2005)

Modeling the organization of the WUSCHEL expression domain in the shoot apical meristem

Paper presented at the 13th International Conference on Intelligent Systems for Molecular Biology, Detroit, MI, JUN 25-29, 2005.Bioinformatics 21 Suppl 1:i232-40. doi: 10.1093/bioinformatics/bti1036


Reddy GV, Heisler MG, Ehrhardt DW, Meyerowitz EM. (2004)

Real-time lineage analysis reveals oriented cell divisions associated with morphogenesis at the shoot apex of Arabidopsis thaliana

Development 131(17):4225-4237. doi: 10.1242/dev.01261

Ohno CK, Reddy GV, Heisler MG, Meyerowitz EM. (2004)

The Arabidopsis JAGGED gene encodes a zinc finger protein that promotes leaf tissue development

Development 131(5):1111-1122. doi: 10.1242/dev.00991


Heisler MG, Atkinson A, Bylstra YH, Walsh R, Smyth DR. (2001)

SPATULA, a gene that controls development of carpel margin tissues in Arabidopsis, encodes a bHLH protein.

Development 128(7):1089-1098.


Mau SL, Anderson MA, Heisler M, Haring V, McClure BA, Clarke AE. (1991)

Molecular and evolutionary aspects of self-incompatibility in flowering plants.

Symp. Soc. Exp. Biol. 45:245-269.

Europe PMC

Bhatia et al., (2016)